Intrauterine insemination
The Intrauterine Insemination ( IUI ) is a method of assisted fertilization , which is usually the artificial insemination is attributed. As a rule, medical staff transfer the sperm cells into the uterine cavity (uterus) using a catheter at the time of conception and are therefore closer to the or possibly the matured egg cell (s) than in the context of natural fertilization immediately after sexual intercourse .
The method is used when sexual intercourse should not take place, for example in the case of a sperm donation , but also in the event of problems with sexual intercourse ( cohabitation disorders ) or a reduced number of functioning sperm cells ( oligospermia ). The probable time of ovulation is estimated beforehand by means of hormone and ultrasound examinations. Often times, egg maturation and ovulation are also induced with medication.
Sometimes during intrauterine insemination, the sperm cells obtained are selected in the laboratory before being introduced into the female body . During this process, the sperm cells already go through the maturation process ( capacitation ), which normally only takes place in the female genital tract.
In most cases, this type of insemination is preceded by hormonal stimulation ; this leads to multiple births in around 20% of all cases .
Success rate
The likelihood that a pregnancy will actually occur as a result of intrauterine insemination depends on numerous factors, for example also on the man's health impairment, which is often the reason for performing an IUI.
According to the University of Bonn, the success rate of intrauterine insemination varies between 5% and 10% per cycle, depending on the indication. The chance of fertilization therefore decreases after the first three attempts.
According to a study that evaluated the data from 1998 to 2010 by the Wiesbaden fertility center, the woman's age is also very important. Accordingly, depending on the age of the woman, the following values were determined for pregnancy:
| Age of woman | Pregnancies per treatment cycle (rounded) |
|---|---|
| <24 | 20% |
| 25-29 | 13% |
| 30-34 | 11% |
| 35-39 | 9% |
| 40-41 | 9% |
| 42-43 | 6% |
| > 43 | 3% |
Source: Obstetrics Frauenheilkd. , 2013 Aug, 73 (8), pp. 808–811, PMC 3859121 (free full text)
See also
literature
- Martius, Breckwoldt, Pfleiderer (Hrsg.): Textbook of gynecology and obstetrics . 2nd Edition. Thieme, Stuttgart / New York 1996, ISBN 3-13-118902-9 .