Isohydria

Isohydria denotes the same (Greek "iso-" = "equal") pH value of two reference systems.

A frequent application in pharmacy is the adjustment of the pH value of eye drops to the physiological pH value (pH 7.4).

This condition is required (in addition to e.g. isotonicity , freedom from particles, sterility ) above all for preparations for use on the eye in order to avoid irritation.

Often, however, isohydria is not particularly beneficial for drug stability - here, euhydria is consulted, which represents a compromise between tolerance, drug stability and drug penetration .

Individual evidence

^ Silvia Grabs: Dosage Forms . 6th edition. Deutscher Apotheker Verlag, Stuttgart 2015, ISBN 978-3-7692-6085-4 , p. 482 .
↑ Lippold, Müller-Goymann, Schubert: Bauer / Frömming / Führer - Pharmaceutical Technology . 10th edition. Deutscher Apotheker Verlag, Stuttgart 2017, ISBN 978-3-8047-3268-1 , p. 408 f .
^ Alfred Fahr: Voigt - Pharmaceutical Technology . 12th edition. Deutscher Apotheker Verlag, Stuttgart 2015, ISBN 978-3-7692-6194-3 , p. 495 .

[1] Silvia Grabs: Dosage Forms . 6th edition. Deutscher Apotheker Verlag, Stuttgart 2015, ISBN 978-3-7692-6085-4 , p. 482 .

[2] Lippold, Müller-Goymann, Schubert: Bauer / Frömming / Führer - Pharmaceutical Technology . 10th edition. Deutscher Apotheker Verlag, Stuttgart 2017, ISBN 978-3-8047-3268-1 , p. 408 f .

[3] Alfred Fahr: Voigt - Pharmaceutical Technology . 12th edition. Deutscher Apotheker Verlag, Stuttgart 2015, ISBN 978-3-7692-6194-3 , p. 495 .