James Preston
James Preston is the name of
- James Preston (actor) (born 1988), American actor
- James H. Preston (1860–1938), American politician, Mayor of Baltimore
- James Moore Preston (1873–1962), American painter and illustrator
- James Patton Preston (1774–1843), American politician
- James Preston (cricketer) (1792-1842), English cricketer
- James B. Preston (1926-2004), American neurophysiologist