James Sinclair
James Sinclair is the name of the following people:
- James Sinclair (fur trader) (1811-1856), Canadian fur trader and explorer
- James Sinclair (botanist) (1913–1968), Scot, British from Orkney , later in Singapore
- James Sinclair (politician) (1908-1984), Canadian politician
- James Sinclair (soccer player) (born 1987), English soccer player
- James H. Sinclair (1871–1943), American politician