John O'Brien
John O'Brien is the name of the following people:
- John O'Brien (Bishop) († 1767), Irish Roman Catholic Bishop
- John O'Brien (politician, 1794) (1794–1855) Irish politician
- John O'Brien (politician, 1847) (1847-1917), Canadian politician
- John O'Brien (politician, 1866) (1866–1932), Australian politician
- John O'Brien (Admiral) (1918–1996), Vice Admiral in the Canadian Armed Forces
- John O'Brien (rower) (1927-1995), New Zealand rower
- John O'Brien (politician, 1932) (1932–1985), American politician
- John O'Brien (writer) (1960–1994), American writer
- John O'Brien (politician, 1962) (born 1962), American politician and film director
- John O'Brien (soccer player) (born 1977), American soccer player
- John O'Brien-Docker (1938–2017), British musician, songwriter, arranger and band leader
- John A. O'Brien , American politician
- John Ambrose O'Brien (1885–1968), Canadian industrialist and founder of the Canadiens de Montréal
- John B. O'Brien (1884–1936), American actor and film director of the silent film era
- John F. O'Brien († 1927), American businessman and politician
- John L. O'Brien (1911–2007), American politician
- John P. O'Brien (1873–1951), American politician
- John P. O'Brien (translator) (* 1963), translator and poet
