Keratocystic odontogenic tumor

Classification according to ICD-10
K09.0	Developmental odontogenic cysts
ICD-10 online (WHO version 2019)

An odontogenic keratocyst , formerly also called a keratocystic odontogenic tumor , or primordial cyst , is an odontogenic cyst . The cyst is a cavity in the jawbone that is lined with a multilayered keratinizing squamous epithelium . It occurs preferentially in the lower jaw (60–80%) and more frequently in men in the second, third and fifth decades of life. The cyst is characterized by locally aggressive but slow growth. After surgical removal, the recurrence rate is high at approx. 40–60%, which is explained on the one hand by frequently present daughter cysts (satellite system) on the edge and on the other hand by remaining epithelial residues postoperatively. It is therefore recommended to mill out the neighboring bone. Adjuvant measures, e.g. B. instillation of Carnoy's solution appear to reduce the rate of recurrence. Therefore, a six-monthly check-up is recommended.

The diagnosis can only be made histologically. Keratocystic odontogenic tumors are rare. A keratocystic odontogenic tumor can develop into an ameloblastoma , while malignant degeneration into squamous cell carcinoma occurs very rarely.

Multiple keratocystic odontogenic tumors are a typical sign of Gorlin-Goltz syndrome .

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1. ↑ N. Schwenzer, M. Ehrenfeld: Tooth-Oral-Kieferheilkunde. 2010.
2. ↑ J. Freyschmidt, H. Ostertag, G. Jundt: Bone tumors, with jaw tumors: Clinic · Radiology · Pathology. Springer Verlag, ISBN 3-540-75153-X , p. 956.
3. ↑ N. Jakse: Jaw cysts differential diagnoses and therapy. (PDF; 241 kB) University Clinic for Dentistry, Oral and Maxillofacial Medicine, Graz
4. ↑ Norbert Schwenzer: Tooth-mouth-jaw medicine: Dental surgery. Georg Thieme Verlag, 2009, ISBN 978-3-13-116964-8 , pp. 184–.

This article is about a health issue. It is not used for self-diagnosis and does not replace a diagnosis by a doctor. Please note the information on health issues !