Kinetochor
| Parent |
| Centromere |
| Subordinate |
| Protein complexes |
| Gene Ontology |
|---|
| QuickGO |
As kinetochore (to ancient Greek κίνησις kinesis , movement 'and χῶρος Choroš , place') is according to recent terminology , a special plate-like or semi-spherical structure of proteins referred to and DNA segments corresponding to the centromere is seated laterally and nuclear division operations as a starting point for the fibers of the spindle apparatus is used.
In the past, the term kinetochore was mostly used synonymously with centromere , for the primary constriction point of a chromosome or the attachment point of spindle fibers.
After microtubules of the spindle fibers of both poles are bound to the kinetochores, a protein complex begins to break the bond between the sister chromatids on the centromere of a chromosome. Only when the sister chromatids no longer adhere to one another can they be drawn via the microtubules to the opposite poles of the spindle apparatus during the early anaphase of mitosis . The kinetochores are therefore an essential element for the process of dividing the genetic material into daughter nuclei.
Individual evidence
- ↑ Jochen Graw: Genetics . Springer, 2010, ISBN 978-3-642-04998-9 ( page 227 in the Google book search).