Cutaneous lymphoma

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Classification according to ICD-10
C84 Peripheral and cutaneous T-cell lymphomas
ICD-10 online (WHO version 2019)

A cutaneous lymphoma ( Latin cutis: skin ) is a lymphoma that develops in the skin. These primarily cutaneous lymphomas must be differentiated from lymphomas of other origins (mostly the lymph nodes ), which can also affect the skin secondarily.

Lymphomas can generally originate from T-lymphocytes ( T-cell lymphomas ) or B-lymphocytes ( B-cell lymphomas ). The latter is rarely the case with purely cutaneous lymphomas. Like other tumor diseases, cutaneous lymphomas can be malignant (malignant) or benign (benign), although the latter can also be a preliminary stage that can later degenerate further.

The most common malignant cutaneous T-cell lymphoma is mycosis fungoides . The other malignant cutaneous T-cell lymphomas are divided into CD30-positive (prognostically more favorable) and CD30-negative (prognostically less favorable).

B-cell lymphomas can also develop primarily in the skin. However, this is only very rarely the case (e.g. immunocytoma , germinal center lymphoma, large-cell B-cell lymphoma ).

Benign lymphomas ( pseudolymphomas ) include lymphocytoma and lymphomatoid papulosis .

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