Lewes (disambiguation)
Lewes means:
- a city in England, see Lewes
 - Lewes (constituency) , a constituency for the British House of Commons
 - a location in the US state of Delaware, see Lewes (Delaware)
 - a river in British Columbia, Canada, see Lewes (river)
 - a district in the county of East Sussex, England, see Lewes District
 - an English writer, literary critic and philosopher, see George Henry Lewes (1817–1878)