Littoral cell angioma

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Classification according to ICD-10
D13 Benign new formation of other and imprecisely designated parts of the digestive system
D13.9 Inaccurate locations within the digestive system
- spleen
ICD-10 online (WHO version 2019)
Photomicrograph of a littoral cell angioma. HE staining .

The littoral cell angioma (engl. Littoral cell angioma ) is a benign tumor of the sinus lining cells in the red pulp of the spleen . The first description was made in 1991 by S. Falk et al. After examining 200 spleen tumors . The tumor shows specific morphological and immunohistochemical properties ( CD 68, CD31). The name is derived from wall cells in the spleen sinus of the red pulp, which are often referred to as "bank cells". The term bank cells was translated by Falk as “littoral cells”. There is evidence of an association between the littoral cell angioma and other malignant tumor diseases.

literature

  • S. Falk, HJ Stutte, G. Frizzera: Littoral cell angioma: a novel splenic vascular lesion demonstrating histiocytic differentiation. In: Am J Surg Pathol 1991; 15, pp. 1023-1033. PMID 1928554