Luis Guzmán (disambiguation)
Luis Guzmán is the name of the following people:
- Luis Guzmán (born 1957), American actor
- Luis Enríquez de Guzmán (around 1600 – after 1661), Spanish officer and colonial administrator, viceroy of New Spain and Peru
- Luis Méndez de Haro y Guzmán (1598–1661), Spanish politician
- Luis Muñoz de Guzmán (1735–1808), Spanish officer and colonial administrator, governor of Chile