Lymphogranuloma venereum

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Classification according to ICD-10
A55 Lymphogranuloma venereum
ICD-10 online (WHO version 2019)

Lymphogranuloma venereum (also venereous granuloma , venereal lymph node inflammation , lymphopathia venerea , lymphogranuloma inguinale , lymphogranulomatosis inguinalis and Nicolas Durand Favre disease ) is a sexually transmitted disease that is rare in the western world and more common in the tropics . The disease is one of the so-called classic sexually transmitted diseases. The pathogens, first discovered as a species of chlamydia by Yoneji Miyagawa (1885–1959) and initially called Miyagawanella lymphogranulomatosis and later Calymmatobacterium granulomatis, are the serotypes L1-L3 of Chlamydia trachomatis .

Clinical picture

Lymph node swelling of the groin in lymphogranuloma venereum

At the point of contact (genital, oral, rectal) small painless ulcers form , which regress spontaneously after 10-14 days. Then the regional lymph nodes (genital and / or groin area in men and genital and / or perineum area in women) swell painfully within one to four weeks ( lymphadenitis ). The skin can turn blue-red in these areas.

If left untreated, this disease can develop into a chronic stage. After five to ten years, the lymphatic system ( lymphatic system ) and genital lymphedema can continue to become blocked for decades . Chronic ulcers in the intestinal area and on the genital organs are signs of a very advanced course of the disease.

General symptoms are fever, joint, muscle and headache.

therapy

Treatment with macrolides and tetracyclines . All sex partners should undergo treatment (post-exposure prophylaxis).

prevention

An effective but not 100% protection are condoms .

Reporting requirement

According to the Austrian Venereal Diseases Act, the disease Lymphogranuloma inguinale is subject to a limited reporting obligation ( Section 4 in conjunction with Section 1 Venereal Diseases Act).

In Switzerland, the positive laboratory analytical finding for laboratories is notifiable and that by following the Epidemics Act (EpG) in connection with the epidemic Regulation and Annex 3 of the Regulation of EDI on the reporting of observations of communicable diseases of man .

Web links

Individual evidence

  1. Birgit Adam : The punishment of Venus. A cultural history of venereal diseases. Orbis, Munich 2001, ISBN 3-572-01268-6 , pp. 14 and 22.
  2. Barbara I. Tshisuaka: Miyagawa, Yoneji. In: Werner E. Gerabek , Bernhard D. Haage, Gundolf Keil , Wolfgang Wegner (eds.): Enzyklopädie Medizingeschichte. De Gruyter, Berlin / New York 2005, ISBN 3-11-015714-4 , p. 1001.