MSL
MSL is an abbreviation for:
- Major Soccer League , American indoor soccer league
- Mars Science Laboratory , NASA Mars mission
- Materials Science Laboratory , experiment on board the International Space Station (ISS)
- Mean Sea Level ("mean sea level"), see sea level
- mIRC Scripting Language , script language of the IRC client mIRC
- Moisture Sensitivity Level (“moisture sensitivity threshold”) in semiconductor technology
- Mzansi Super League , South African professional league in Twenty20 cricket
