Mammorenal Syndrome

As mammorenales syndrome the common occurrence of is malformation of the kidney with the system of excess nipples ( polythelia ), respectively. An accumulation has been described in individual families.

Clinical significance

The clinical significance of the syndrome is controversial. Several studies showed no or only a small association between polythelia and malformations of the genitourinary system, which is why it was concluded that further diagnostic examinations are not necessary in otherwise clinically normal newborns with polythelia. Other authors document a significant incidence of kidney malformations in children with polythelia and therefore call for detailed, further diagnostics in this group of people.

Individual evidence

↑ Meggyessy V, Méhes K: Association of supernumerary nipples with renal anomalies . In: J. Pediatr. . 111, No. 3, September 1987, pp. 412-3. PMID 3305849 .
↑ Brown J, Schwartz RA: Supernumerary nipples and renal malformations: a family study . In: Journal of Cutaneous Medicine and Surgery . 8, No. 3, 2004, pp. 170-2. doi : 10.1007 / s10227-003-0166-1 . PMID 15578130 .
↑ Urbani CE, Betti R: Familial aberrant mammary tissue: a clinicoepidemiological survey of 18 cases . In: Dermatology . 190, No. 3, 1995, pp. 207-9. PMID 7599382 .
↑ Bortz J, Parker S, Ray TL: Lack of associated renal anomalies in familial polythelia . In: Am. J. Dis. Child. . 143, No. 8, August 1989, p. 883. PMID 2756962 .
↑ Grotto I, Browner-Elhanan K, Mimouni D, Varsano I, Cohen HA, Mimouni M: Occurrence of supernumerary nipples in children with kidney and urinary tract malformations . In: Pediatric Dermatology . 18, No. 4, 2001, pp. 291-4. PMID 11576400 .
↑ Ferrara P, Giorgio V, Vitelli O, et al. : Polythelia: still a marker of urinary tract anomalies in children? . In: Scand. J. Urol. Nephrol. . 43, No. 1, 2009, pp. 47-50. doi : 10.1080 / 00365590802442086 . PMID 18836948 .
↑ Urbani CE, Betti R: Accessory mammary tissue associated with congenital and hereditary nephrourinary malformations . In: International Journal of Dermatology . 35, No. 5, May 1996, pp. 349-52. PMID 8734657 .

[1] Meggyessy V, Méhes K: Association of supernumerary nipples with renal anomalies . In: J. Pediatr. . 111, No. 3, September 1987, pp. 412-3. PMID 3305849 .

[2] Brown J, Schwartz RA: Supernumerary nipples and renal malformations: a family study . In: Journal of Cutaneous Medicine and Surgery . 8, No. 3, 2004, pp. 170-2. doi : 10.1007 / s10227-003-0166-1 . PMID 15578130 .

[3] Urbani CE, Betti R: Familial aberrant mammary tissue: a clinicoepidemiological survey of 18 cases . In: Dermatology . 190, No. 3, 1995, pp. 207-9. PMID 7599382 .

[4] Bortz J, Parker S, Ray TL: Lack of associated renal anomalies in familial polythelia . In: Am. J. Dis. Child. . 143, No. 8, August 1989, p. 883. PMID 2756962 .

[5] Grotto I, Browner-Elhanan K, Mimouni D, Varsano I, Cohen HA, Mimouni M: Occurrence of supernumerary nipples in children with kidney and urinary tract malformations . In: Pediatric Dermatology . 18, No. 4, 2001, pp. 291-4. PMID 11576400 .

[6] Ferrara P, Giorgio V, Vitelli O, et al. : Polythelia: still a marker of urinary tract anomalies in children? . In: Scand. J. Urol. Nephrol. . 43, No. 1, 2009, pp. 47-50. doi : 10.1080 / 00365590802442086 . PMID 18836948 .

[7] Urbani CE, Betti R: Accessory mammary tissue associated with congenital and hereditary nephrourinary malformations . In: International Journal of Dermatology . 35, No. 5, May 1996, pp. 349-52. PMID 8734657 .