Meige syndrome
| Classification according to ICD-10 | |
|---|---|
| G24.4 | Idiopathic orofacial dystonia |
| ICD-10 online (WHO version 2019) | |
Also known as idiopathic orofacial dyskinesia , blepharospasm-oromandibular dystonia, or Brueghel syndrome , Meige syndrome is a rare neurological disorder. It was named after the French neurologist and art historian Henry Meige (1866–1940), a student of Jean-Martin Charcot , who described the clinical picture in detail in 1910. The name Brueghel Syndrome refers to the painting The Yawn , which is attributed to the Flemish painter Pieter Brueghel the Elder .
This must be distinguished from the Nonne-Milroy-Meige syndrome or Meige disease , a very rare congenital form of lymphedema .
Symptoms
The disease, which is classified as a dystonia, manifests itself in symmetrical, convulsive, uncontrollable contractions of the facial, jaw and throat muscles, which can lead to involuntary movements such as jaw opening, sticking out the tongue, pulling back the lips and blepharospasm , i.e. convulsive closure of the eyes. It mainly affects women in their seventh decade of life.
therapy
A therapy attempt can be undertaken with benzodiazepines , baclofen , anticholinergics or botulinum toxin . Blepharospasm is one of the most common indications for the use of botulinum toxin; a good improvement can be achieved in more than 90% of the treated cases.
source
- K. Poeck, W. Hacke: Neurology . 1998, Springer-Verlag Berlin, ISBN 3-540-63028-7 .
- Website of the University of Jena
Individual evidence
- ↑ H. Meige: Les convulsions de la face, une forme clinique de convulsion faciale, bilaterale et mediane. In: Rev Neurol (Paris) . tape 20 , 1910, pp. 437-443 .
