Monocistronic mRNA

In genetics, monocistronic is an mRNA that encodes a single cistron that corresponds to a gene. These mRNAs therefore only contain one open reading frame . In contrast to the monocistronic eukaryotic mRNAs, the predominantly polygenic (polycistronic) mRNAs of the prokaryotes are encoded by several different genes. In some viruses , translation of their entire genome results in a monocistronic polyprotein .

swell

↑ Kirk U. Knowlton, Cornel Badorff, Gil-Hwan Lee, Barry J. Lamphear, Maryann E. Martone, Kevin P. Campbell, Robert E. Rhoads: Enteroviral protease 2A cleaves dystrophin: Evidence of cytoskeletal disruption in an acquired cardiomyopathy. In: Nature Medicine. 5, p. 320, doi : 10.1038 / 6543 .

[1] Kirk U. Knowlton, Cornel Badorff, Gil-Hwan Lee, Barry J. Lamphear, Maryann E. Martone, Kevin P. Campbell, Robert E. Rhoads: Enteroviral protease 2A cleaves dystrophin: Evidence of cytoskeletal disruption in an acquired cardiomyopathy. In: Nature Medicine. 5, p. 320, doi : 10.1038 / 6543 .