Fournier gangrene

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Classification according to ICD-10
N49.80 Fournier gangrene in men
N76.80 Fournier gangrene in women
ICD-10 online (WHO version 2019)
A 48 year old patient with Fournier gangrene after removal of necrotic tissue.
The same patient six months after a skin graft.

The Fournier gangrene , including Crohn Fournier , is a rare special form of necrotizing fasciitis of the groin and genital area . The infection , usually a mixed infection with different both aerobic and anaerobic bacterial pathogens , originates in the skin, the urinary tract or the anorectal area ( anus or rectum ). The mortality of Fournier gangrene can be up to 67%, depending on the clinical stage and the time of diagnosis, despite adequate antibiotics and radical surgical therapy; rapid diagnosis and therapy can reduce mortality to below 4%.

H. Baurienne first described the disease. The disease is named after Jean Alfred Fournier (1832–1915), who in 1883 described a case in an otherwise healthy young man.

In 2000, a retrospective study was published which identified 1726 relevant cases from the English-language articles in the Medline database over the past 50 years. This showed, among other things, that the diagnosis is primarily clinical, that the disease is probably underdiagnosed in women and that treatment methods such as hyperbaric oxygen therapy or radical surgery are controversial.

Individual evidence

  1. MK Moslemi, MA Sadighi Gilani et al: Fournier gangrene presenting in a patient with undiagnosed rectal adenocarcinoma: a case report. In: Cases journal. Volume 2, 2009, pp. 9136, ISSN  1757-1626 . doi: 10.1186 / 1757-1626-2-9136 . PMID 20062653 . PMC 2803933 (free full text).
  2. ^ Baurienne H: Sur une plaie contuse qui s'est terminee par le sphacele de la scrotum. In: J Med Chir Pharm . tape 20 , 1764, pp. 251-256 .
  3. Gangrène foudroyante de la verge. In: La semaine médicale. Paris, 1883, 3, p. 345.
  4. ^ N. Eke: Fournier's gangrene: a review of 1726 cases. In: Br J Surg . tape 87 , no. 6 , 2000, pp. 718-728 , PMID 10848848 .