Panomic

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Panomics (from the Greek pan 'everything' and -omics ) denotes the systems biology use of data from various areas such as genetics , transcriptomics , proteomics and metabolomics . It plays a role especially in personalized oncology and personalized medicine in general. The most recent addition was metabolomics.

Studies in the 1990s on gene expression and polymorphisms are considered to be the beginning of the use of panomics and thus also of big data in biology .

The American Society of Clinical Oncology (ASCO) defines panomics as:

"The interaction of all biological functions within a cell and with other body functions, combining data collected by targeted tests ... and global assays (such as genome sequencing) with other patient-specific information."

"The interaction of all biological functions within a cell and with other body functions, the combination of data acquisition from targeted tests [...] and global projects [...] with other patient-specific information"

- American Society of Clinical Oncology: Accelerating Progress Against Cancer: ASCO's blueprint for transforming clinical and translational cancer research.

Individual evidence

  1. ↑ Seetharaman Vaidyanathan: Metabolome Analyzes :. Springer Science & Business Media, 2006, ISBN 978-0-387-25240-7 , p. 2.
  2. ↑ Soren Brunak: Cancer Panomics: Computational Methods And Infrastructure For Integrative Analysis of Cancer Highthroughput "OMICS" Data. (PDF) Accessed November 5, 2018 .
  3. ↑ PSB 2014: Cancer Panomics Session. Retrieved May 11, 2018 .
  4. ↑ Yuquan Wei, Shengyong Yang, Huixiao Hong, Feixiong Cheng: Individualized network-based drug repositioning infrastructure for precision oncology in the panomics era . In: Briefings in Bioinformatics . tape 18 , no. 4 , July 1, 2017, ISSN  1467-5463 , p. 682-697 , doi : 10.1093 / bib / bbw051 ( oup.com [accessed December 19, 2018]).
  5. ↑ Charanjit Sandhu, Alia Qureshi, Andrew Emili: Panomics for Precision Medicine . In: Trends in Molecular Medicine . tape 24 , no. 1 , January 2018, ISSN  1471-4914 , p. 85-101 , doi : 10.1016 / j.molmed.2017.11.001 , PMID 29217119 , PMC 5839674 (free full text).
  6. ↑ “Panomics” in Personalized Medicine. Retrieved May 11, 2018 .
  7. ↑ Charanjit Sandhu, Alia Qureshi, Andrew Emili: Panomics for Precision Medicine . In: Trends in Molecular Medicine . tape 24 , no. 1 , January 2018, ISSN  1471-4914 , p. 85-101 , doi : 10.1016 / j.molmed.2017.11.001 , PMID 29217119 , PMC 5839674 (free full text) - ( elsevier.com [accessed May 11, 2018]).
  8. ↑ American Society of Clinical Oncology: Accelerating Progress Against Cancer: ASCO's blueprint for transforming clinical and translational cancer research . 2011, Glossary, p. 28 ( asco.org [PDF; accessed on September 13, 2013]).