-omics

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-omik ( Greek -ομική , female; English -omics) identifies, as a suffix, sub-areas of modern biology that deal with the analysis of groups of similar individual elements.

The proteomics dealing for example with the proteome ( English : proteome ), the total of all proteins , which at a defined time in a cell , a cell group, an organ or an organism present. Analogously, the entirety of the genes of an organism is referred to as the genome , and the subject area for its research is genomics . Human Protein Atlas is a website about the representation of the proteome.

The aim of functional genomics is to elucidate the function of as many genes as possible in an organism, primarily combining genomics, transcriptomics, proteomics, metabolomics and large-scale mutant analyzes. The evaluation of all individual results requires bioinformatic methods.

The aim of systems biology is to get an integrated picture of all regulatory processes across all levels, from the genome to the proteome, to the organelles, to the behavior and biomechanics of the entire organism.

Some of the most common terms are listed in the table. However, there are now a large number of other terms that have hardly found their way into the German vocabulary: for example Interactome-Interactomics, Physiome-Physiomics.

The pair of terms toponome- toponomics is also occasionally counted among the -omics. This is wrong because the syllable "-nom" is formed from the Greek noun nomos .

List of specialties
Area of ​​Expertise entirety Single element
Genomics Genome gene
Metabolomics Metabolome Metabolite (metabolite)
Proteomics Proteome protein
Lipidomics Lipidoma Lipid
Systemics Effect structure Transmission link
Transcriptomics Transcriptome Transcript ( mRNA )
Glycomic Glycan Polysaccharides
Fluxomics Fluxoma catalyzed conversions of substances and their speed
Interactomics Interactome Interaction of molecules
Panomic Panom all previous together

See also

Individual evidence

  1. ^ Hauke ​​Holtorf, Marie-Christine Guitton, Ralf Reski (2002): Plant functional genomics. In: Natural Sciences. Vol. 89, pp. 235-249.