Photoretinitis

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The photoretinitis or blue light hazard is a photochemical damage to the retina (retinal) by high-energy blue visible light (maximum at 440 nm ).

effect

In addition to the damage caused by IR - and UV - radiation arising to the lens or cornea usually by thermal processes and absorbed on the cornea (combustion, turbidity and inflammation), penetrates blue (short wavelength light) through the cornea and reach the retina . Oxidation can cause irreversible damage to receptors .

Occur

There are only a few diagnosed cases, as the damage is usually associated with IR or UV injuries and is usually superimposed. However, with the increase in strong artificial blue light sources such as light-emitting diodes and lasers , the risk is increasing. It is believed that macular degeneration is a result of chronic exposure.

further reading

  • EL Pautler, M. Morita, D. Beezley: Hemoprotein (s) mediate blue light damage in the retinal pigment epithelium. In: Photochemistry and photobiology. Volume 51, Number 5, May 1990, pp. 599-605, ISSN  0031-8655 . PMID 2367557 .
  • Y. Seko, J. Pang, et al. a .: Blue light-induced apoptosis in cultured retinal pigment epithelium cells of the rat. In: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes archive for clinical and experimental ophthalmology. Volume 239, Number 1, January 2001, pp. 47-52, ISSN  0721-832X . PMID 11271461 .

Individual evidence

  1. ↑ PV Algvere, J. Marshall, S. Seregard: Age-related maculopathy and the impact of blue light hazard. In: Acta ophthalmologica Scandinavica. Volume 84, Number 1, February 2006, pp. 4-15, ISSN  1395-3907 . doi : 10.1111 / j.1600-0420.2005.00627.x . PMID 16445433 . (Review).
  2. ↑ SM Meyers, MA Ostrovsky, RF Bonner: A model of spectral filtering to reduce photochemical damage in age-related macular degeneration. In: Transactions of the American Ophthalmological Society. Volume 102, 2004, pp. 83-93, ISSN  0065-9533 . PMID 15747748 . PMC 1280090 (free full text).
  3. ↑ JM Nolan, P. O'Reilly et al. a .: Augmentation of macular pigment following implantation of blue light-filtering intraocular lenses at the time of cataract surgery. In: Investigative ophthalmology & visual science. Volume 50, Number 10, October 2009, pp. 4777-4785, ISSN  1552-5783 . doi : 10.1167 / iovs.08-3277 . PMID 19628740 .

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