Pilomatrix carcinoma

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Classification according to ICD-10
C44.9 Malignant neoplasm of the skin, unspecified
ICD-10 online (WHO version 2019)

A pilomatrix carcinoma (also matric carcinoma, malignant pilomatrixoma) is a very rare malignant skin tumor of the matrix cells of the hair follicle . It is the malignant variant of pilomatrixoma and occurs predominantly in male patients between the ages of 40 and 50. Pilomatrix carcinoma tends to be locally aggressive and resistant to radiation therapy, as well as to form distant metastases . Therapy consists in removing the tumor with a large safety margin. The recurrence rate is 50–60% of cases.

The pilomatrix carcinoma was first described by N. Gromiko in 1927. Pilomatrix carcinomas also occur in dogs .

Individual evidence

  1. ↑ a b S. Yadia u. a .: Pilomatrix carcinoma of the thoracic spine: case report and review of the literature. In: The journal of spinal cord medicine. Volume 33, Number 3, 2010, pp. 272-277, ISSN  1079-0268 . PMID 20737803 . PMC 2920123 (free full text). (Review).
  2. ^ A b P. Altmeyer: Pilomatrix carcinoma. (see literature )
  3. ↑ N. Gromiko: On the knowledge of the malignant transformation of the calcified skin epithelioma. In: Virchows Archiv 265.1 (1927): pp. 103-116. ( online )
  4. ↑ EE Carroll et al. a .: Malignant pilomatricoma in 3 dogs. In: Veterinary pathology. Volume 47, Number 5, September 2010, pp. 937-943, ISSN  1544-2217 . doi : 10.1177 / 0300985810371310 . PMID 20466858 . (free full text)

literature

  • P. Altmeyer: Pilomatrix carcinoma . In: Encyclopedia of Dermatology, Venereology, Allergology, Environmental Medicine (online edition)