Potentially inadequate medication

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Under potentially inappropriate medications (PIM or English also Potentially Inappropriate Medication ) is the account of their pharmacokinetic and pharmacodynamic unsuitable effects for the elderly drugs or combinations of drugs. In 1991 the Beers list was drawn up by the American geriatrician Mark H. Beers. It is a list of drugs that patients over 65 years of age should not receive. In 2003 the list was updated. It is primarily a matter of drugs, which, especially in the elderly, lead to increased adverse drug effects or for which alternative drugs with fewer side effects are available.

Situation in Germany

For a long time there was no comparable list of drugs for Germany, even if this would have been desirable due to the different market and the different prescribing practices. In 2005, 20% of patients over 65 years of age in Germany were prescribed at least one drug from the Beers list. In 2010, a research team led by the Wuppertal pharmacologist Petra A. Thürmann published the Priscus list , which tries to adapt the Beers list to national characteristics.

Synonyms and related terms

The term and acronym PIM have only been in use since around 1991.

literature

  • Beers, MH et al. Explicit criteria for determining inappropriate medication use in nursing home residents. Arch Intern Med . 1991 Sep; 151 (9): 1825-32
  • Fick, DM et al. Updating the Beers criteria for potentially inappropriate medication use in older adults: results of a US consensus panel of experts. Arch Intern Med. 2003 Dec 8-22; 163 (22): 2716-24

Web links

Individual evidence

  1. Internet page for the PRISCUS list
  2. Holt et al. Potentially inadequate medication for the elderly: The PRISCUS list Dtsch Arztebl Int 2010; 107 (31-32): 543-51