Potentially inadequate medication
Under potentially inappropriate medications (PIM or English also Potentially Inappropriate Medication ) is the account of their pharmacokinetic and pharmacodynamic unsuitable effects for the elderly drugs or combinations of drugs. In 1991 the Beers list was drawn up by the American geriatrician Mark H. Beers. It is a list of drugs that patients over 65 years of age should not receive. In 2003 the list was updated. It is primarily a matter of drugs, which, especially in the elderly, lead to increased adverse drug effects or for which alternative drugs with fewer side effects are available.
Situation in Germany
For a long time there was no comparable list of drugs for Germany, even if this would have been desirable due to the different market and the different prescribing practices. In 2005, 20% of patients over 65 years of age in Germany were prescribed at least one drug from the Beers list. In 2010, a research team led by the Wuppertal pharmacologist Petra A. Thürmann published the Priscus list , which tries to adapt the Beers list to national characteristics.
Synonyms and related terms
The term and acronym PIM have only been in use since around 1991.
literature
- Beers, MH et al. Explicit criteria for determining inappropriate medication use in nursing home residents. Arch Intern Med . 1991 Sep; 151 (9): 1825-32
- Fick, DM et al. Updating the Beers criteria for potentially inappropriate medication use in older adults: results of a US consensus panel of experts. Arch Intern Med. 2003 Dec 8-22; 163 (22): 2716-24
Web links
- Medical prescriptions of potentially inadequate medication in the elderly An analysis based on the PRISCUS list Dtsch Ärztebl Int 2012 109 (5)
- Polypharmacotherapy in old age: fewer drugs are often more (Dtsch Ärztebl 2012 (109))
- Unsuitable pharmaceuticals for seniors (Pharmazeutische Zeitung 11 (2010))
- Drug therapy safety of older patients (PhDs at UKE 2014, PhD student: Beate Wickop)
- Original article Potentially inadequate medication for the elderly: The PRISCUS list Dtsch Ärztebl Int 2010 107 (31-32)
- PRISCUS list
- Rx trend report from the Central Institute for Statutory Health Insurance in the Federal Republic of Germany (ZI) (Jan. - June 2012)
- German version of the current Beers list (2005) in Der Arzneimittelbrief No. 4, April 2012
Individual evidence
- ↑ Internet page for the PRISCUS list
- ↑ Holt et al. Potentially inadequate medication for the elderly: The PRISCUS list Dtsch Arztebl Int 2010; 107 (31-32): 543-51