Sebostasis (from Latin sebum "sebum" and ancient Greek στάσις " stasis ") describes the reduced sebum secretion of the skin. The consequences of sebostasis can be dry, dry skin ( xerosis cutis , also known as xeroderma ) and dull hair . The opposite, increased sebum secretion, is called seborrhea .
The cause is an underfunction of the sebum glands. It is typical of atopy and leads to increased water loss through the skin . In the context of atopic eczema , an impairment of the epidermal lipid metabolism (delta-6 desaturase defect) is held responsible for this hypofunction. About 80% of the sebostasis occurs as a result of reduced sebum secretion in old age. The decrease in sebum production is explained here by a decreasing release of androgens . In addition, red-haired and blonde people suffer more from this skin condition due to their genetic predisposition.
Symptom of illness
The reduction in sebum leads to a disruption of the skin's barrier function, which causes it to lose more water. Clinically, the skin appears dry and low in fat and the hair appears dull. In addition, the skin is highly sensitive to the sun and has little ability to neutralize alkalis . Often, the skin's sweat production is also reduced. Circumscribed peeling of the skin occurs, especially on the lateral parts of the upper arms, the lower legs and the trunk. Dry skin is often itchy. Since it has lost part of its protective function due to the lack of a layer of fat, it can also be colonized with the bacterium Staphylococcus aureus .
As a rule, mainly external applications such as moisturizing cleansing products (creams, ointments and emulsions of the water-in-oil type) are used therapeutically. In severe cases, simultaneous treatment of the underlying disease (e.g. atopic dermatitis ) is appropriate.
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