Sigrun Smola

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Sigrun Smola (née Hess) is a doctor and virologist . She is professor and director of the Institute for Virology at the Saarland University Medical Center . Her research focuses on tumor diseases caused by human papilloma viruses (HPV) - in addition to cervical cancer , other types of cancer - and new therapeutic approaches to them. She and her team are also studying the conditions under which viral infections and other complications occur after organ transplants .

Career

Sigrun Heß first studied psychology at the University of Heidelberg from 1984 , but switched to human medicine there in 1985 . After graduating in 1991, she worked as a research assistant at the Institute for Immunology at LMU Munich from 1992 , where she also received her doctorate in 1993. In 1995 she moved to the Institute of Virology at the Cologne University Hospital , where she headed an independent junior research group from 1999 to 2003. During this time she was funded by the Ministry of Science in North Rhine-Westphalia through the Research Innovation Program . In 2001 she passed the examination to become a specialist in microbiology , virology and infection epidemiology and completed her habilitation the following year in virology, followed by a Heisenberg scholarship at the University of Cologne from 2003 to 2004. She then took on a professorship and deputy head of the institute for Virology.

In 2009, Smola accepted an appointment as professor at the Institute for Virology at the Saarland University Hospital in Saarbrücken. There she held the offices of deputy dean of research and vice-president for studies and teaching.

Smola is a member of several professional societies, including chair of the Central Commission for Biosafety and board member of the Society for Virology as well as deputy spokeswoman for the Virology working group in the Experimental Cancer Research Department of the German Cancer Society.

Smola's working group at the Saarland University Medical Center deciphered a previously unknown mechanism in the skin papilloma virus that increases the cancer-promoting effect of UV light . In the joint project xploit , her institute is involved in developing models to better predict complications after transplants - such as viral infections - in the treated people and thus counteract them. In the field of health services research , Smola is analyzing the effectiveness of preventive measures against cervical cancer for the first time as a model region for the Saarland .

Fonts (selection)

  • Stimulation of human monocytes via their complement receptor for C3b (CR1, CD35) to release interleukin-1, prostaglandin E2 and oxygen radicals . (Dissertation, University of Cologne 2003). Heidelberg 1992.
  • The importance of the CD40L-CD40 interaction for the function and defense of virally transformed cells . (Habilitation thesis). Cologne 2001.
  • Anna M. Marthaler, Marta Podgorska, Pascal Feld, Alina Fingerle, Katrin Knerr-Rupp: Identification of C / EBPα as a novel target of the HPV8 E6 protein regulating miR-203 in human keratinocytes . In: PLOS Pathogens . tape 13 , no. 6 , June 22, 2017, ISSN  1553-7374 , p. e1006406 , doi : 10.1371 / journal.ppat.1006406 , PMID 28640877 , PMC 5481020 (free full text) - ( plos.org [accessed on March 20, 2020]). <

Web links

Individual evidence

  1. ↑ a b Virologists at Saar University discover a new mechanism that promotes the development of skin cancer. Retrieved March 20, 2020 .
  2. ↑ Working group of Prof. Dr. med. Sigrun Smola. In: uniklinikum-saarland.de. Retrieved March 20, 2020 .
  3. ↑ Sigrun Heß: Stimulation of human monocytes via their complement receptor for C3b (CR1, CD35) to release interleukin-1, prostaglandin E2 and oxygen radicals . Heidelberg, Univ., Diss., 1993, 1992 ( uni-heidelberg.de [accessed on March 20, 2020]).
  4. ↑ The importance of the CD40L-CD40 interaction for the function and defense of virally transformed cells. Retrieved March 20, 2020 .
  5. ↑ a b Tabular curriculum vitae of Univ.-Prof. Dr. med. Sigrun Smola. In: zkbs-online.de. 2017, accessed March 20, 2020 .
  6. ↑ ZKBS - composition. Retrieved March 20, 2020 .
  7. ↑ Board of Directors | Gesellschaft für Virologie eV Accessed March 20, 2020 .
  8. ^ German Cancer Society - Department of Experimental Cancer Research (AEK) - German Cancer Society. Retrieved March 20, 2020 .
  9. ↑ Anna M. Marthaler, Marta Podgorska, Pascal Feld, Alina Fingerle, Katrin Knerr-Rupp: Identification of C / EBPα as a novel target of the HPV8 E6 protein regulating miR-203 in human keratinocytes . In: PLOS Pathogens . tape 13 , no. 6 , June 22, 2017, ISSN  1553-7374 , p. e1006406 , doi : 10.1371 / journal.ppat.1006406 , PMID 28640877 , PMC 5481020 (free full text) - ( plos.org [accessed on March 20, 2020]).
  10. ↑ Fraunhofer Institute for Biomedical Technology IBMT: Medical Application - XplOit. Retrieved on March 20, 2020 (German).
  11. ↑ PRÄZIS - Prevention of cervical cancer and its precursors in women in Saarland - G-BA Innovation Fund. Retrieved March 20, 2020 .
personal data
SURNAME Smola, Sigrun
ALTERNATIVE NAMES Hess, Sigrun (maiden name)
BRIEF DESCRIPTION Virologist and professor at Saarland University
DATE OF BIRTH 20th century