Single copy gene

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A single-copy gene is a gene that only occurs in a single copy in the entire genome .

Examples of single-copy genes:

  • The gene coding for PrP protein called PRNP , which is located on the short arm of the 20th chromosome in humans and comprises around 750 base pairs .
  • The b-actin sequence, which is highly conserved in many organisms and can thus be used to differentiate the genomes of different organisms.

Individual evidence

  1. ^ DM Coen: Quantitation of rare DNAs by PCR. In: Current protocols in immunology / edited by John E. Coligan ... [et al.]. Chapter 10 May 2001, S. Unit 10.21, ISSN  1934-368X . doi : 10.1002 / 0471142735.im1021s24 . PMID 18432686 .