Spruill
Spruill is the family name of the following people:
- Godfrey Spruill (approx. 1650 – approx. 1719), Scottish-American doctor
- Hezekiah Spruill (1732–1804), planter and member of the North Carolina Provincial Congress
- Hezekiah G. Spruill (1808–1874), Confederate General in the American Civil War
- Lionell Spruill (* 1946), American politician
- Steven G. Spruill (* 1946), American writer
