Tenase complex
The tenase complex is a component of secondary hemostasis (plasmatic coagulation) composed of several factors . The Tenase complex consists of four factors:
- Christmas factor (factor IX),
- Antihemophilic globulin A (factor VIII),
- Phospholipids and
- Calcium ions
The tenase complex is located on the surface of activated platelets, since this is where the necessary phospholipids can be found in the cell membrane . Ultimately, its task is to activate the Stuart-Prower factor (factor X), which in turn is part of the prothrombinase complex. Since thrombin, as the central point of plasmatic coagulation, is directly and indirectly responsible for the activation of the tenase complex, and this then partially activates the prothrombinase complex, which ultimately activates thrombin again, it is a self-reinforcing mechanism.
Individual evidence
- ↑ Bernd Pötzsch, Katharina Madlener: Haemostaseology. Basics, diagnostics and therapy Springer, 2010, p. 241, ISBN 978-3-642-01543-4
- ↑ Bernd Pötzsch, Katharina Madlener: Haemostaseology. Basics, diagnostics and therapy Springer, 2010, p. 137, ISBN 978-3-642-01543-4