Tracheal cancer

Classification according to ICD-10
C33	Malignant neoplasm of the trachea
ICD-10 online (WHO version 2019)

The position of the trachea (bottom in the center of the picture)

The windpipe, with the larynx (above) and bronchial system

Tracheal cancer (also Tracheakarzinom , rare Trachealkarzinom ) is a rare, to the head and neck tumors belonging, cancer of the trachea ( trachea ). The majority of these are epidermoid tumors, followed by adenocarcinomas .

Epidemiology

Tracheal cancer is an extremely rare disease. According to the Federal Statistical Office, more than 40,000 German citizens died of lung cancer in 2006, whereas only 40 died of tracheal cancer. The incidence is around 1 per 1,000,000 population.

etiology

The development of a cancer of the windpipe is generally seen in direct connection with a previous tobacco abuse . Due to the very low incidence, statistically reliable studies that could establish a connection to other exposures are almost impossible to carry out.
In December 2004, the State Social Court of North Rhine-Westphalia (LSG) decided in Essen that tracheal cancer caused by asbestos fibers can be recognized as an occupational disease if there are no economic risk factors in the form of alcohol or cigarette consumption.

therapy

With regard to the treatment of tracheal cancer, due to the low incidence, there is little experience.

As is common with many cancers with solid tumors, three forms of therapy are used.

For treatment with radiation therapy , curative doses in the range of 64 to 70 Gray with a single dose of 2 Gray are chosen.
Surgical removal ( resection ) of the tumor
chemotherapy

literature

G. Holmgren: On the case history of primary tracheal carcinomas. In: European Archives of Oto-Rhino-Laryngology. 122/1929, pp. 145-151.
BCF Ulrich: The importance of panendoscopy for the diagnosis of tumor spread in tumors in the jaw and face area. Dissertation . Eberhard Karls University of Tübingen, 2003.
MRR Moreno et al .: ABS90: Chronic cough as the sole initial manifestation of epidermoid carcinoma of the trachea. In: Primary Care Respiratory Journal. 15/2006, p. 211.
TH Lange et al: Tracheobronchial glomus tumor. In: The Annals of Thoracic Surgery . 70/2000, pp. 292-295.
YM Menaissy et al .: Glomus tumor of the trachea. In: The Annals of Thoracic Surgery. 70/2000, pp. 295-297.
F. Mornex et al. Role of Radiation Therapy in the Treatment of Primary Tracheal Carcinoma. In: International Journal of Radiation Oncology. 41/1998, pp. 299-305.
P. Contencin et al: Squamous cell carcinoma of the trachea in an infant: a case report. In: International Journal of Pediatric Otorhinolaryngology. 43/1998, pp. 163-173.
IG Duarte et al .: Primary Malignant Melanoma of the Trachea. In: The Annals of Thoracic Surgery. 65/1998, pp. 559-560.
JF Pantridge: Primary carcinoma of the trachea. In: British Journal of Surgery . 37/1949, p. 48. PMID 18135655
HC Grillo: Development of tracheal surgery: a historical review. Part 1: techniques of tracheal surgery. In: The Annals of Thoracic Surgery. 75/2003, pp. 610-619.
HC Grillo: Development of tracheal surgery: a historical review. Part 2: treatment of tracheal diseases. In: The Annals of Thoracic Surgery. 75/2003, pp. 1039-1047.
CS Pramesh et al: Is compromising on surgical margins in tracheal resection for cancer justified? In: European Journal of Cardio-Thoracic Surgery . 23/2003, pp. 1077-1078.
KH Kim: Pleomorphic adenoma of the trachea. In: Otolaryngology - Head and Neck Surgery . 123/2000, pp. 147-148.

Web links

Individual evidence

↑ Steven I. Hajdu, Andrew G. Huvos et al. a .: Carcinoma of the trachea. Clinicopathologic study of 41 cases. In: Cancer. 25, 1970, p. 1448, doi : 10.1002 / 1097-0142 (197006) 25: 6 <1448 :: AID-CNCR2820250625> 3.0.CO; 2-N .
↑ Federal Statistical Office Germany Lung cancer is the fourth most common cause of death. ( Memento of February 1, 2010 in the Internet Archive ) Press release of May 25, 2007.
↑ ^a ^b ^c LSG judgment (legally binding) on the recognition of tracheal carcinoma as an occupational disease (BK 4104). Ref .: L 17 U 27/02 of September 22, 2004.
↑ B. Schäfer, P. Hödl: Medical-technical assistance in the modern radiation therapy. Springer, 1999, ISBN 3-540-63834-2 .

[1] Steven I. Hajdu, Andrew G. Huvos et al. a .: Carcinoma of the trachea. Clinicopathologic study of 41 cases. In: Cancer. 25, 1970, p. 1448, doi : 10.1002 / 1097-0142 (197006) 25: 6 <1448 :: AID-CNCR2820250625> 3.0.CO; 2-N .

[2] Federal Statistical Office Germany Lung cancer is the fourth most common cause of death. ( Memento of February 1, 2010 in the Internet Archive ) Press release of May 25, 2007.

[lsg-3] LSG judgment (legally binding) on the recognition of tracheal carcinoma as an occupational disease (BK 4104). Ref .: L 17 U 27/02 of September 22, 2004.

[4] B. Schäfer, P. Hödl: Medical-technical assistance in the modern radiation therapy. Springer, 1999, ISBN 3-540-63834-2 .