Well-Aue reaction

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The Wohl-Aue reaction is a chemical reaction between an aromatic organic nitro compound and aniline or an aniline derivative, in which a phenazine is formed in the presence of a base . An example is the reaction between nitrobenzene and aniline:

Wohl-Aue-reaction Overview reaction

The reaction was named after the two chemists Alfred Wohl and Wilhelm Aue , who first published the process in 1901.

literature

  • Zerong Wang (Ed.): Comprehensive Organic Name Reactions and Reagents . 3 volume set. John Wiley & Sons, Hoboken, NJ 2009, ISBN 978-0-471-70450-8 .

Individual evidence

  1. ↑ a b A. Wohl, W. Aue: On the action of nitrobenzene on aniline in the presence of alkali. In: Chemical Reports . 34, 1901, pp. 2442-2450.
  2. ↑ IJ Pachter, MC Kloetzel: The well-Aue reaction. I. Structure of Benzo [a] phenazine Oxides and Syntheses of 1,6-Dimethoxyphenazine and 1,6-Dichlorophenazine. In: J. Am. Chem. Soc. 73, 1951, pp. 4958-4961, doi: 10.1021 / ja01154a144 .