Young Syndrome
The disease Young's syndrome is the combination of chronic infections of the respiratory tract and decreased fertility in the male. This syndrome was first described by Donald Young in 1970.
Course of disease
Already in their childhood, the patients are noticed by frequently recurring inflammations of the bronchi and paranasal sinuses . There is a cough with sputum . Often bronchiectasis can also be detected. The cause of the decreased fertility is probably a thickening of the sperm secretion . Cystic fibrosis is an important differential diagnosis .
causes
It is believed that Young syndrome can be inherited as an autosomal recessive trait. However, no more cases have been found in people born after 1955. One therefore suspects damage from mercury or other environmental factors.
therapy
For fertility treatment, sperm can be removed and given directly into the egg cell by means of intracytoplasmic sperm injection .
Individual evidence
- ↑ D. Young: Surgical treatment of male infertility . In: J. Reprod. Fertile. tape 23 , no. 3 , December 1970, p. 541-542 , PMID 5497459 .
- ^ A b c Susan Nieschlag, Eberhard Nieschlag, Hermann Behre: Andrology: Fundamentals and clinics of reproductive health of men . Springer, Berlin 2009, ISBN 978-3-540-92962-8 , pp. 277 .
- ^ Young syndrome. In: Online Mendelian Inheritance in Man . (English)
- ↑ WF Hendry, RP A'Hern, PJ Cole: Was Young's syndrome caused by exposure to mercury in childhood? In: BMJ . tape 307 , no. 6919 , 1993, pp. 1579-1582 , PMID 8292944 , PMC 1697782 (free full text).