Cyanide nitroprusside test

The cyanide nitroprusside test is used in the diagnosis of cystinuria , which among other things leads to an increased excretion of the amino acid cystine .

The cystine contained in the urine is qualitatively detected with this test by reducing it to cysteine using cyanide . In the presence of nitroprusside , the solution turns red. A positive test indicates a concentration in the urine of more than 75 mg / l and speaks in favor of the diagnosis of cystinuria. A negative test excludes the presence of a cystinuria with a high probability.

literature

• Christa Schmidt: Genetic defects in renal cystine transport and their significance for cystinuria (PDF) In: Dissertation of the Faculty of Biology at the Eberhard-Karls-Universität Tübingen . P. 133. 2004. Retrieved January 16, 2010.

Individual evidence

1. ^ Erwin Brand, Meyer M. Harris, and Sol Biloon: Cystinuria: The excretion of cystine complex which decomposes in the urine with the liberation of free cystine . In: The Journal of biological chemistry . 1, No. 86, March 1930, pp. 315-331. Retrieved January 16, 2010.
2. ↑ Elaine Worcester: Cystine stones. UpToDate Ver. 17.3 September 2009

This article is about a health issue. It is not used for self-diagnosis and does not replace a diagnosis by a doctor. Please note the information on health issues !