Atlastin-1

ATL1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3Q5D, 3Q5E, 3QNU, 3QOF, 4IDN, 4IDO, 4IDP, 4IDQ
Identifiers
Aliases	ATL1, AD-FSP, FSP1, GBP3, HSN1D, SPG3, SPG3A, atlastin1, Atlastin, atlastin GTPase 1
External IDs	OMIM: 606439; MGI: 1921241; HomoloGene: 9302; GeneCards: ATL1; OMA:ATL1 - orthologs
Gene location (Human)
Chr.	Chromosome 14 (human)
End	50,634,017 bp
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)
End	70,013,191 bp
RNA expression pattern
	Top expressed in
	middle temporal gyrus; ; Brodmann area 23; ; endothelial cell; ; spinal ganglia; ; Brodmann area 46; ; pons; ; superior frontal gyrus; ; entorhinal cortex; ; superior vestibular nucleus; ; prefrontal cortex;
	Top expressed in
	dorsomedial hypothalamic nucleus; ; piriform cortex; ; primary motor cortex; ; ventral tegmental area; ; ventromedial nucleus; ; prefrontal cortex; ; lateral hypothalamus; ; cingulate gyrus; ; subiculum; ; paraventricular nucleus of hypothalamus;
	More reference expression data
	n/a
Gene ontology
Molecular function	nucleotide binding; GTP binding; protein binding; hydrolase activity; GTPase activity; identical protein binding;
Cellular component	cytoplasm; integral component of membrane; axon; Golgi membrane; Golgi apparatus; cell projection; endoplasmic reticulum membrane; endoplasmic reticulum; membrane; Golgi cis cisterna; endoplasmic reticulum tubular network; endoplasmic reticulum tubular network membrane;
Biological process	protein homooligomerization; axonogenesis; endoplasmic reticulum organization; endoplasmic reticulum tubular network membrane organization; metabolism;
	Sources:Amigo / QuickGO
Orthologs
	51062
	73991
	ENSG00000198513
	ENSMUSG00000021066
	Q8WXF7
	Q8BH66
	NM_181598; NM_001127713; NM_015915
	NM_178628
	NP_001121185; NP_056999; NP_853629
	NP_848743
	Wikidata
View/Edit Human	View/Edit Mouse

Atlastin, or Atlastin-1, is a protein that in humans is encoded by the ATL1 gene.^[5]^[6]^[7]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000198513 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000021066 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Hazan J, Lamy C, Melki J, Munnich A, de Recondo J, Weissenbach J (Jan 1994). "Autosomal dominant familial spastic paraplegia is genetically heterogeneous and one locus maps to chromosome 14q". Nat Genet. 5 (2): 163–7. doi:10.1038/ng1093-163. PMID 8252041.{{cite journal}}: CS1 maint: multiple names: authors list (link)
^ Gispert S, Santos N, Damen R, Voit T, Schulz J, Klockgether T, Orozco G, Kreuz F, Weissenbach J, Auburger G (Feb 1995). "Autosomal dominant familial spastic paraplegia: reduction of the FSP1 candidate region on chromosome 14q to 7 cM and locus heterogeneity". Am J Hum Genet. 56 (1): 183–7. PMC 1801298. PMID 7825576.{{cite journal}}: CS1 maint: multiple names: authors list (link)
^ "Entrez Gene: SPG3A spastic paraplegia 3A (autosomal dominant)".

External links

GeneReviews/NCBI/NIH/UW entry on Spastic Paraplegia 3A

References

External links

Further reading