C1QTNF4 (gene)

C1QTNF4
Identifiers
Aliases	C1QTNF4, CTRP4, ZACRP4, C1q and tumor necrosis factor related protein 4, C1q and TNF related 4
External IDs	OMIM: 614911 MGI: 1914695 HomoloGene: 12134 GeneCards: C1QTNF4
Gene location (Human) Chr. Chromosome 11 (human) Band 11p11.2 Start 47,589,667 bp End 47,594,411 bp
Gene location (Mouse) Chr. Chromosome 2 (mouse) Band 2|2 E1 Start 90,716,204 bp End 90,720,869 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in superior frontal gyrus nucleus accumbens putamen caudate nucleus Brodmann area 9 temporal lobe amygdala hippocampus proper hypothalamus substantia nigra Top expressed in superior frontal gyrus olfactory bulb hippocampus proper spermatid cerebellar cortex spermatocyte testicle neural tube mesencephalon hypothalamus More reference expression data BioGPS n/a
Gene ontology Molecular function cytokine activity molecular function Cellular component extracellular region extracellular space Biological process regulation of signaling receptor activity positive regulation of interleukin-6 production positive regulation of interleukin-6-mediated signaling pathway positive regulation of NIK/NF-kappaB signaling signal transduction Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 114900 67445 Ensembl ENSG00000172247 ENSG00000284838 ENSMUSG00000040794 UniProt Q9BXJ3 Q8R066 RefSeq (mRNA) NM_031909 NM_026161 RefSeq (protein) NP_114115 NP_080437 Location (UCSC) Chr 11: 47.59 – 47.59 Mb Chr 2: 90.72 – 90.72 Mb PubMed search
Wikidata
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C1q and tumor necrosis factor related protein 4 is a protein that in humans is encoded by the C1QTNF4 gene.

Further reading

• Li Q, Wang L, Tan W, Peng Z, Luo Y, Zhang Y, Zhang G, Na D, Jin P, Shi T, Ma D, Wang L (2011). "Identification of C1qTNF-related protein 4 as a potential cytokine that stimulates the STAT3 and NF-κB pathways and promotes cell survival in human cancer cells". Cancer Lett. 308 (2): 203–14. doi:10.1016/j.canlet.2011.05.005. PMID 21658842.