Clavaviridae: Difference between revisions
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'''''Clavaviridae''''' is a family of double-stranded viruses that infect archaea. This family was first described by the team led by D. [[ |
'''''Clavaviridae''''' is a family of double-stranded viruses that infect archaea. This family was first described by the team led by D. [[David Prangishvili|Prangishvili]] in 2010. There is one genus in this family (''Clavavirus''). Within this genus, only a single species has been described to date: ''[[Aeropyrum pernix bacilliform virus 1]]''. |
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The name is derived from the [[Latin]] word ''clava'' meaning stick. |
The name is derived from the [[Latin]] word ''clava'' meaning stick. |
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==Virology== |
==Virology== |
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The virons are bacilliform in shape and 143 nanometers (nm) in length and 15.8 nm in diameter.<ref name=Mochizuki2010>{{cite journal |vauthors=Mochizuki T, Yoshida T, Tanaka R, Forterre P, Sako Y, Prangishvili D |title=Diversity of viruses of the hyperthermophilic archaeal genus Aeropyrum, and isolation of the Aeropyrum pernix bacilliform virus 1, APBV1, the first representative of the family ''Clavaviridae'' |journal=Virology |volume=402 |issue=2 |pages=347–54 |year=2010 |pmid=20430412 |doi=10.1016/j.virol.2010.03.046 |url=https://linkinghub.elsevier.com/retrieve/pii/S0042-6822(10)00229-1}}</ref><ref name=struct>{{cite journal|last1=Ptchelkine|first1=D|last2=Gillum|first2=A|last3=Mochizuki|first3=T|last4=Lucas-Staat|first4=S|last5=Liu|first5=Y|last6=Krupovic|first6=M|last7=Phillips|first7=SEV|last8=Prangishvili|first8=D|last9=Huiskonen|first9=JT|title=Unique architecture of thermophilic archaeal virus APBV1 and its genome packaging.|journal=Nature |
The virons are bacilliform in shape and 143 nanometers (nm) in length and 15.8 nm in diameter.<ref name=Mochizuki2010>{{cite journal |vauthors=Mochizuki T, Yoshida T, Tanaka R, Forterre P, Sako Y, Prangishvili D |title=Diversity of viruses of the hyperthermophilic archaeal genus Aeropyrum, and isolation of the Aeropyrum pernix bacilliform virus 1, APBV1, the first representative of the family ''Clavaviridae'' |journal=Virology |volume=402 |issue=2 |pages=347–54 |year=2010 |pmid=20430412 |doi=10.1016/j.virol.2010.03.046 |url=https://linkinghub.elsevier.com/retrieve/pii/S0042-6822(10)00229-1}}</ref><ref name=struct>{{cite journal|last1=Ptchelkine|first1=D|last2=Gillum|first2=A|last3=Mochizuki|first3=T|last4=Lucas-Staat|first4=S|last5=Liu|first5=Y|last6=Krupovic|first6=M|last7=Phillips|first7=SEV|last8=Prangishvili|first8=D|last9=Huiskonen|first9=JT|title=Unique architecture of thermophilic archaeal virus APBV1 and its genome packaging.|journal=Nature Communications|date=10 November 2017|volume=8|issue=1|pages=1436|doi=10.1038/s41467-017-01668-0|pmid=29127347}}</ref> One end is pointed and the other is rounded. The structure of the APBV1 virion has been solved by cryo-electron microscopy to near-atomic resolution, revealing how the helical particle is built from an alpha-helical major capsid protein with a unique structural fold.<ref name=struct /> |
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The genome is a circular double-stranded DNA molecule of 5.3 kb. It does not integrate into the host genome. |
The genome is a circular double-stranded DNA molecule of 5.3 kb. It does not integrate into the host genome. |
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Infection with this virus does not cause host cell lysis. |
Infection with this virus does not cause host cell lysis. |
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{{taxonbar}} |
{{taxonbar}} |
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[[Category:Double-stranded DNA viruses]] |
[[Category:Double-stranded DNA viruses]] |
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[[Category:Virus families]] |
[[Category:Virus families]] |
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{{virus-stub}} |
{{virus-stub}} |
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Revision as of 04:38, 25 November 2017
| Claviviridae | |
|---|---|
| Virus classification | |
| Group: | Group I (dsDNA)
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| Order: | Unassigned
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| Family: | Clavaviridae
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| Genera | |
Clavaviridae is a family of double-stranded viruses that infect archaea. This family was first described by the team led by D. Prangishvili in 2010. There is one genus in this family (Clavavirus). Within this genus, only a single species has been described to date: Aeropyrum pernix bacilliform virus 1.
The name is derived from the Latin word clava meaning stick.
Virology
The virons are bacilliform in shape and 143 nanometers (nm) in length and 15.8 nm in diameter.[1][2] One end is pointed and the other is rounded. The structure of the APBV1 virion has been solved by cryo-electron microscopy to near-atomic resolution, revealing how the helical particle is built from an alpha-helical major capsid protein with a unique structural fold.[2]
The genome is a circular double-stranded DNA molecule of 5.3 kb. It does not integrate into the host genome.
Infection with this virus does not cause host cell lysis.
References
- ^ Mochizuki T, Yoshida T, Tanaka R, Forterre P, Sako Y, Prangishvili D (2010). "Diversity of viruses of the hyperthermophilic archaeal genus Aeropyrum, and isolation of the Aeropyrum pernix bacilliform virus 1, APBV1, the first representative of the family Clavaviridae". Virology. 402 (2): 347–54. doi:10.1016/j.virol.2010.03.046. PMID 20430412.
- ^ a b Ptchelkine, D; Gillum, A; Mochizuki, T; Lucas-Staat, S; Liu, Y; Krupovic, M; Phillips, SEV; Prangishvili, D; Huiskonen, JT (10 November 2017). "Unique architecture of thermophilic archaeal virus APBV1 and its genome packaging". Nature Communications. 8 (1): 1436. doi:10.1038/s41467-017-01668-0. PMID 29127347.
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