Nidogen-2: Difference between revisions
Content deleted Content added
m →Further reading: Task 7c: repair/replace et al. in cs1 author/editor parameters; |
Citation bot (talk | contribs) Add: s2cid, doi-access. | Use this bot. Report bugs. | Suggested by Headbomb | #UCB_toolbar |
||
(14 intermediate revisions by 8 users not shown) | |||
Line 1: | Line 1: | ||
{{Short description|Protein-coding gene in the species Homo sapiens}} |
|||
{{PBB|geneid=22795}} |
|||
{{Infobox_gene}} |
|||
'''Nidogen-2''' is a [[protein]] |
'''Nidogen-2''', also known as '''osteonidogen''', is a [[basal lamina]] [[protein]] of the [[nidogen]] family. It was the second nidogen to be described after [[nidogen-1]] (entactin). Both play key roles during late [[embryonic development]].<ref>{{cite journal | vauthors = Miosge N, Holzhausen S, Zelent C, Sprysch P, Herken R | title = Nidogen-1 and nidogen-2 are found in basement membranes during human embryonic development | journal = The Histochemical Journal | volume = 33 | issue = 9–10 | pages = 523–30 | year = 2002 | pmid = 12005023 | doi = 10.1023/A:1014995523521 | s2cid = 818451 }}</ref> In humans it is encoded by the ''NID2'' [[gene]].<ref name="pmid9733643">{{cite journal | vauthors = Kohfeldt E, Sasaki T, Göhring W, Timpl R | title = Nidogen-2: a new basement membrane protein with diverse binding properties | journal = Journal of Molecular Biology | volume = 282 | issue = 1 | pages = 99–109 | date = Sep 1998 | pmid = 9733643 | doi = 10.1006/jmbi.1998.2004 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: NID2 nidogen 2 (osteonidogen)| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=22795}}</ref> |
||
⚫ | |||
<!-- The PBB_Summary template is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. --> |
|||
⚫ | |||
{{PBB_Summary |
|||
| section_title = |
|||
| summary_text = Basement membranes, which are composed of type IV collagens (see MIM 120130), laminins (see LAMC1; MIM 150290), perlecan (HSPG2; MIM 142461), and nidogen (see NID1; MIM 131390), are thin pericellular protein matrices that control a large number of cellular activities, including adhesion, migration, differentiation, gene expression, and apoptosis [supplied by OMIM].<ref name="entrez" /> |
|||
}} |
|||
⚫ | |||
⚫ | |||
⚫ | |||
⚫ | |||
{{refbegin | 2}} |
{{refbegin | 2}} |
||
⚫ | * {{cite journal | vauthors = Ulazzi L, Sabbioni S, Miotto E, Veronese A, Angusti A, Gafà R, Manfredini S, Farinati F, Sasaki T, Lanza G, Negrini M | title = Nidogen 1 and 2 gene promoters are aberrantly methylated in human gastrointestinal cancer | journal = Molecular Cancer | volume = 6 | issue = 1 | pages = 17 | year = 2007 | pmid = 17328794 | pmc = 1831485 | doi = 10.1186/1476-4598-6-17 | doi-access = free }} |
||
{{PBB_Further_reading |
|||
* {{cite journal | vauthors = Nischt R, Schmidt C, Mirancea N, Baranowsky A, Mokkapati S, Smyth N, Woenne EC, Stark HJ, Boukamp P, Breitkreutz D | title = Lack of nidogen-1 and -2 prevents basement membrane assembly in skin-organotypic coculture | journal = The Journal of Investigative Dermatology | volume = 127 | issue = 3 | pages = 545–54 | date = Mar 2007 | pmid = 17008882 | doi = 10.1038/sj.jid.5700562 | doi-access = free }} |
|||
| citations = |
|||
* {{cite journal | vauthors = Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M | title = Towards a proteome-scale map of the human protein-protein interaction network | journal = Nature | volume = 437 | issue = 7062 | pages = 1173–8 | date = Oct 2005 | pmid = 16189514 | doi = 10.1038/nature04209 | bibcode = 2005Natur.437.1173R | s2cid = 4427026 }} |
|||
⚫ | |||
*{{cite journal |
* {{cite journal | vauthors = Miosge N, Sasaki T, Timpl R | title = Evidence of nidogen-2 compensation for nidogen-1 deficiency in transgenic mice | journal = Matrix Biology | volume = 21 | issue = 7 | pages = 611–21 | date = Nov 2002 | pmid = 12475645 | doi = 10.1016/S0945-053X(02)00070-7 }} |
||
*{{cite journal |
* {{cite journal | vauthors = Tu H, Sasaki T, Snellman A, Göhring W, Pirilä P, Timpl R, Pihlajaniemi T | title = The type XIII collagen ectodomain is a 150-nm rod and capable of binding to fibronectin, nidogen-2, perlecan, and heparin | journal = The Journal of Biological Chemistry | volume = 277 | issue = 25 | pages = 23092–9 | date = Jun 2002 | pmid = 11956183 | doi = 10.1074/jbc.M107583200 | doi-access = free }} |
||
*{{cite journal |
* {{cite journal | vauthors = Sasaki T, Göhring W, Mann K, Brakebusch C, Yamada Y, Fässler R, Timpl R | title = Short arm region of laminin-5 gamma2 chain: structure, mechanism of processing and binding to heparin and proteins | journal = Journal of Molecular Biology | volume = 314 | issue = 4 | pages = 751–63 | date = Dec 2001 | pmid = 11733994 | doi = 10.1006/jmbi.2001.5176 }} |
||
*{{cite journal |
* {{cite journal | vauthors = Sasaki T, Göhring W, Miosge N, Abrams WR, Rosenbloom J, Timpl R | title = Tropoelastin binding to fibulins, nidogen-2 and other extracellular matrix proteins | journal = FEBS Letters | volume = 460 | issue = 2 | pages = 280–4 | date = Oct 1999 | pmid = 10544250 | doi = 10.1016/S0014-5793(99)01362-9 | s2cid = 25139630 | doi-access = }} |
||
*{{cite journal |
* {{cite journal | vauthors = Bonaldo MF, Lennon G, Soares MB | title = Normalization and subtraction: two approaches to facilitate gene discovery | journal = Genome Research | volume = 6 | issue = 9 | pages = 791–806 | date = Sep 1996 | pmid = 8889548 | doi = 10.1101/gr.6.9.791 | doi-access = free }} |
||
*{{cite journal |vauthors=Miosge N, Holzhausen S, Zelent C, etal |title=Nidogen-1 and nidogen-2 are found in basement membranes during human embryonic development. |journal=Histochem. J. |volume=33 |issue= 9-10 |pages= 523–30 |year= 2002 |pmid= 12005023 |doi=10.1023/A:1014995523521 }} |
|||
*{{cite journal |vauthors=Tu H, Sasaki T, Snellman A, etal |title=The type XIII collagen ectodomain is a 150-nm rod and capable of binding to fibronectin, nidogen-2, perlecan, and heparin. |journal=J. Biol. Chem. |volume=277 |issue= 25 |pages= 23092–9 |year= 2002 |pmid= 11956183 |doi= 10.1074/jbc.M107583200 }} |
|||
*{{cite journal |vauthors=Sasaki T, Göhring W, Mann K, etal |title=Short arm region of laminin-5 gamma2 chain: structure, mechanism of processing and binding to heparin and proteins. |journal=J. Mol. Biol. |volume=314 |issue= 4 |pages= 751–63 |year= 2002 |pmid= 11733994 |doi= 10.1006/jmbi.2001.5176 }} |
|||
*{{cite journal |vauthors=Sasaki T, Göhring W, Miosge N, etal |title=Tropoelastin binding to fibulins, nidogen-2 and other extracellular matrix proteins. |journal=FEBS Lett. |volume=460 |issue= 2 |pages= 280–4 |year= 1999 |pmid= 10544250 |doi=10.1016/S0014-5793(99)01362-9 }} |
|||
*{{cite journal | author=Bonaldo MF, Lennon G, Soares MB |title=Normalization and subtraction: two approaches to facilitate gene discovery. |journal=Genome Res. |volume=6 |issue= 9 |pages= 791–806 |year= 1997 |pmid= 8889548 |doi=10.1101/gr.6.9.791 }} |
|||
}} |
|||
{{refend}} |
{{refend}} |
||
[[Category:Extracellular matrix proteins]] |
|||
{{gene-14-stub}} |
|||
[[Category:Genes on human chromosome 14]] |
|||
<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. --> |
|||
{{PBB_Controls |
|||
| update_page = yes |
|||
| require_manual_inspection = no |
|||
| update_protein_box = yes |
|||
| update_summary = yes |
|||
| update_citations = yes |
|||
}} |
Latest revision as of 00:08, 3 December 2023
NID2 | |||||||||||||||||||||||||||||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Identifiers | |||||||||||||||||||||||||||||||||||||||||||||||||||
Aliases | NID2, NID-2, nidogen 2 | ||||||||||||||||||||||||||||||||||||||||||||||||||
External IDs | OMIM: 605399 MGI: 1298229 HomoloGene: 40575 GeneCards: NID2 | ||||||||||||||||||||||||||||||||||||||||||||||||||
| |||||||||||||||||||||||||||||||||||||||||||||||||||
| |||||||||||||||||||||||||||||||||||||||||||||||||||
| |||||||||||||||||||||||||||||||||||||||||||||||||||
| |||||||||||||||||||||||||||||||||||||||||||||||||||
| |||||||||||||||||||||||||||||||||||||||||||||||||||
Wikidata | |||||||||||||||||||||||||||||||||||||||||||||||||||
|
Nidogen-2, also known as osteonidogen, is a basal lamina protein of the nidogen family. It was the second nidogen to be described after nidogen-1 (entactin). Both play key roles during late embryonic development.[5] In humans it is encoded by the NID2 gene.[6][7]
References[edit]
- ^ a b c GRCh38: Ensembl release 89: ENSG00000087303 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000021806 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ Miosge N, Holzhausen S, Zelent C, Sprysch P, Herken R (2002). "Nidogen-1 and nidogen-2 are found in basement membranes during human embryonic development". The Histochemical Journal. 33 (9–10): 523–30. doi:10.1023/A:1014995523521. PMID 12005023. S2CID 818451.
- ^ Kohfeldt E, Sasaki T, Göhring W, Timpl R (Sep 1998). "Nidogen-2: a new basement membrane protein with diverse binding properties". Journal of Molecular Biology. 282 (1): 99–109. doi:10.1006/jmbi.1998.2004. PMID 9733643.
- ^ "Entrez Gene: NID2 nidogen 2 (osteonidogen)".
Further reading[edit]
- Ulazzi L, Sabbioni S, Miotto E, Veronese A, Angusti A, Gafà R, Manfredini S, Farinati F, Sasaki T, Lanza G, Negrini M (2007). "Nidogen 1 and 2 gene promoters are aberrantly methylated in human gastrointestinal cancer". Molecular Cancer. 6 (1): 17. doi:10.1186/1476-4598-6-17. PMC 1831485. PMID 17328794.
- Nischt R, Schmidt C, Mirancea N, Baranowsky A, Mokkapati S, Smyth N, Woenne EC, Stark HJ, Boukamp P, Breitkreutz D (Mar 2007). "Lack of nidogen-1 and -2 prevents basement membrane assembly in skin-organotypic coculture". The Journal of Investigative Dermatology. 127 (3): 545–54. doi:10.1038/sj.jid.5700562. PMID 17008882.
- Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (Oct 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
- Miosge N, Sasaki T, Timpl R (Nov 2002). "Evidence of nidogen-2 compensation for nidogen-1 deficiency in transgenic mice". Matrix Biology. 21 (7): 611–21. doi:10.1016/S0945-053X(02)00070-7. PMID 12475645.
- Tu H, Sasaki T, Snellman A, Göhring W, Pirilä P, Timpl R, Pihlajaniemi T (Jun 2002). "The type XIII collagen ectodomain is a 150-nm rod and capable of binding to fibronectin, nidogen-2, perlecan, and heparin". The Journal of Biological Chemistry. 277 (25): 23092–9. doi:10.1074/jbc.M107583200. PMID 11956183.
- Sasaki T, Göhring W, Mann K, Brakebusch C, Yamada Y, Fässler R, Timpl R (Dec 2001). "Short arm region of laminin-5 gamma2 chain: structure, mechanism of processing and binding to heparin and proteins". Journal of Molecular Biology. 314 (4): 751–63. doi:10.1006/jmbi.2001.5176. PMID 11733994.
- Sasaki T, Göhring W, Miosge N, Abrams WR, Rosenbloom J, Timpl R (Oct 1999). "Tropoelastin binding to fibulins, nidogen-2 and other extracellular matrix proteins". FEBS Letters. 460 (2): 280–4. doi:10.1016/S0014-5793(99)01362-9. PMID 10544250. S2CID 25139630.
- Bonaldo MF, Lennon G, Soares MB (Sep 1996). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Research. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.