Radicicol

Radicicol
Names
	IUPAC name (1aR,2E,4E,14R,15aR)-8-chloro-9,11-dihydroxy-14-methyl-1a,14,15,15a-tetrahydro-6H-oxireno[e][2]benzoxacyclotetradecine-6,12(7H)-dione
Identifiers
CAS Number	12772-57-5 ;
3D model (JSmol)	Interactive image;
ChEBI	CHEBI:556075;
ChEMBL	ChEMBL453386;
ChemSpider	16735913 ;
ECHA InfoCard	100.170.695
PubChem CID	6323491;
CompTox Dashboard (EPA)	DTXSID2042692 ;
	InChI InChI=1S/C18H17ClO6/c1-9-6-15-14(25-15)5-3-2-4-10(20)7-11-16(18(23)24-9)12(21)8-13(22)17(11)19/h2-5,8-9,14-15,21-22H,6-7H2,1H3/b4-2+,5-3- Key: WYZWZEOGROVVHK-HZDAAVBUSA-N ; Key: WYZWZEOGROVVHK-HZDAAVBUBT; Key: WYZWZEOGROVVHK-HZDAAVBUSA-N;
	SMILES O=C1\C=C\C=C/C3OC3CC(C)OC(=O)c2c(O)cc(O)c(Cl)c2C1;
Properties
Chemical formula	C18H17ClO6
Molar mass	364.78 g·mol−1
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

Radicicol, also known as monorden, is a natural product that binds to Hsp90 (Heat Shock Protein 90) and alters its function. HSP90 client proteins play important roles in the regulation of the cell cycle, cell growth, cell survival, apoptosis, angiogenesis and oncogenesis.

Further reading