Alpha lipoprotein

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In the medical literature, the term alpha lipoprotein (s) is usually used synonymously with high density lipoprotein (HDL). This synonymous use is widespread, but strictly speaking not correct from a laboratory chemical point of view. In the Anglo-American literature, the term high-density alpha-lipoprotein is also used synonymously.

In column chromatography , the proportions of lipoproteins are essentially shown as alpha lipoproteins (i.e. α bands), which correspond to HDL in ultracentrifugation . In terms of laboratory chemistry, however, there is no strict identity between the terms "alpha lipoproteins" and "HDL" due to the completely different test methods. Clinically, the alpha lipoproteins (analogous to HDL) are regarded as the non- atherosclerosis- inducing components of the lipoproteins.

Genetic changes can lead to disorders in the formation of alpha lipoproteins. Tangier's disease is an example here .

See also

Individual evidence

  1. ^ HR Schumacher et al.: Handbook of Hematologic Pathology. Informa Health Care, 2000, ISBN 0-8247-0170-4 , pp. 161-162. (books.google.de)
  2. ↑ R. Nader et al.: Handbook of Lipoprotein Testing. Amer. Assoc. for Clinical Chemistry, 1997, ISBN 1-890883-35-2 , pp. 223ff. (books.google.de)
  3. ↑ M. Gowan: Determination of HDL in whole blood. Patent: EP0428980, 1991. (freepatentsonline.com) and (freepatentsonline.com)
  4. ^ Roche Lexikon Medizin , Urban & FischerVerlag, 2003, ISBN 3-437-15150-9 , p. 1119. (books.google.de)