Basic therapy

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A basic therapy is a form of therapy , the stereotype for a long time, so regularly carried out according to a fixed pattern. It is therefore independent of short-term fluctuating influences such as B. the current severity of the disease or the food consumption of the patient. In the case of basic drug therapy, one often speaks of basic medication .

In addition to the basic therapy, a bolus therapy based on the patient's current condition can be specified. A well-known example is the basic bolus therapy for patients with diabetes mellitus .

Many autoimmunological diseases are also treated with basic therapy that is combined with bolus therapy, which is also called relapse therapy . The goal of basic therapy is to maintain remission , while the goal of relapse therapy is to induce remission.

Basic therapy for rheumatic diseases

In rheumatic diseases, basic therapy is given with disease-modifying anti-rheumatic drugs (DMARD). This long-term form of therapy aims to contain the further course of the disease and the associated complaints and restrictions.

The basic therapeutic agents used for rheumatic diseases (slow-acting long-term therapeutic agents ) are so-called progression-slowing anti-inflammatory drugs that are used as second-line drugs over a longer period of time. In contrast to the first-line drugs , which include analgesics , non-steroidal anti-inflammatory drugs and steroidal anti-inflammatory drugs (corticosteroids), the basic drugs act on the disease process and slow down the progression of the disease. They have a positive influence on the course of the disease in the short and long term and not only alleviate the symptoms. Combination therapy with second- and first-line agents is often necessary.

Web links

Individual evidence

  1. Buer, Jonas Kure. 2015. "A history of the term“ DMARD ” ." Inflammopharmacology 23 (4): 163-171. doi : 10.1007 / s10787-015-0232-5 .
  2. Wolfgang Miehle: Joint and spinal rheumatism. Eular Verlag, Basel 1987, ISBN 3-7177-0133-9 , pp. 76-78.