Fcγ receptor IIa
| Fcγ receptor IIa | ||
|---|---|---|
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| according to PDB 1FCG | ||
| other names |
CDw32, Fc-gamma RII-a, Fc-gamma-RIIa, FcRII-a, Low affinity immunoglobulin gamma Fc region receptor II-a |
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| Properties of human protein | ||
| Mass / length primary structure | 317 amino acids , 35,001 Da | |
| Identifier | ||
| External IDs | ||
The Fcγ receptor IIa (synonym CD32a ) is a surface protein from the group of Fc receptors .
properties
The Fcy receptor IIA binds as Fcy receptor , the Fc region of immunoglobulin G with lower affinity and of monocytes , neutrophils and eosinophils formed. It is involved in phagocytosis after opsonization . Fcγ receptor IIA is glycosylated and phosphorylated .
Web links
Individual evidence
- ↑ M. Arman, K. Krauel: Human platelet IgG Fc receptor FcγRIIA in immunity and thrombosis. In: Journal of thrombosis and haemostasis: JTH. Volume 13, Number 6, June 2015, pp. 893-908, doi : 10.1111 / jth.12905 , PMID 25900780 .