Hematopoietic precursor cell antigen CD34
Hematopoietic precursor cell antigen CD34 | ||
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other names |
CD34, Hematopoietic progenitor cell antigen CD34 |
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Properties of human protein | ||
Mass / length primary structure | 385 amino acids , 40,716 Da | |
Identifier | ||
External IDs |
CD34 is a surface protein and cell adhesion molecule .
properties
CD34 is a sialomucin and is produced by hematopoietic progenitor cells and endothelial cells of various tissues . In the bone marrow, it binds hematopoietic stem cells to the extracellular matrix or to stromal cells . It binds selectins and is glycosylated and phosphorylated .
Web links
Individual evidence
- ↑ SG Furness, K. McNagny: Beyond mere markers: functions for CD34 family of sialomucins in hematopoiesis. In: Immunologic research. Volume 34, Number 1, 2006, pp. 13-32, doi : 10.1385 / IR: 34: 1: 13 , PMID 16720896 .