Dienophile

Structure of PTAD

Dienophile is the name given to alkenes that are suitable reactants for 1,3- dienes in a Diels-Alder reaction .

Most dienophiles have electron-withdrawing substituents , such as. B. a carbonyl group, an electron-deficient π-bond. A strong negative mesomeric and inductive effect of the substituents on the double bond is decisive for the strength of the dienophilic character. These dienophiles readily react with electron-rich dienes.

The rarer case of an electron-rich dienophile that reacts with an electron-poor diene is also possible. The most reactive dienophile currently known is PTAD .

Individual evidence

1. ↑ Entry on dienophile . In: IUPAC Compendium of Chemical Terminology (the “Gold Book”) . doi : 10.1351 / goldbook.D01700 Version: 2.1.5.