Dressler syndrome

Classification according to ICD-10
I24.1	Post myocardial infarction syndrome Dressler syndrome II
ICD-10 online (WHO version 2019)

The Dressler's syndrome is a special form of pericarditis , ie an inflammation of the pericardium , the first time in 1956 by William Dressler (1890-1969), the then director of the Maimonides Medical Center , Brooklyn has been described. It is not caused by pathogens , but occurs in 3% of cases 1–6 weeks after tissue destruction of deeper lying muscles in a heart attack , after heart injuries or after heart operations (post-myocardiotomy syndrome).

In contrast to pericarditis epistenocardica , an acute inflammation in the infarct area, Dressler's syndrome is a late immunological reaction on the pericardium after the formation of heart muscle cell antibodies weeks to months after an infarction.

The affected people develop a fever , leukocytosis (changes in the blood count due to inflammation) and often pericardial effusion . Larger effusions affect the heart and must therefore be punctured ; Mechanically disruptive adhesions between the two pericardial leaves can also occur. Next comes a pleurisy with consecutive pleural effusions on.

NSAIDs come therapeutically , e.g. B. ibuprofen and colchicine are used. Glucocorticoids are no longer recommended due to the risk of scar thinning with subsequent aneurysm development or rupture.

literature

^ H. Renz-Polster, J. Braun: Basic textbook internal medicine. 2nd edition, Verlag Urban & Fischer, Munich 2001, ISBN 3-437-41051-2 , p. 78.
↑ B. Maisch, K. Karatolios: New possibilities for diagnosis and therapy of pericarditis . In: The internist . tape 49 , no. 1 , January 2008, ISSN 0020-9554 , p. 17-26 , doi : 10.1007 / s00108-007-1961-3 ( [1] ).
^ Adler Y., et al .: 2015 ESC Guidelines for the diagnosis and management of pericardial diseases: The Task Force for the Diagnosis and Management of Pericardial Diseases of the European Society of Cardiology (ESC). Endorsed by: The European Association for Cardio-Thoracic Surgery (EACTS). In: Eur Heart J . No. 36 , 2015, p. 2921-2964 .

[1] H. Renz-Polster, J. Braun: Basic textbook internal medicine. 2nd edition, Verlag Urban & Fischer, Munich 2001, ISBN 3-437-41051-2 , p. 78.

[DOI10.1007/s00108-007-1961-3-2] B. Maisch, K. Karatolios: New possibilities for diagnosis and therapy of pericarditis . In: The internist . tape 49 , no. 1 , January 2008, ISSN 0020-9554 , p. 17-26 , doi : 10.1007 / s00108-007-1961-3 ( [1] ).

[3] Adler Y., et al .: 2015 ESC Guidelines for the diagnosis and management of pericardial diseases: The Task Force for the Diagnosis and Management of Pericardial Diseases of the European Society of Cardiology (ESC). Endorsed by: The European Association for Cardio-Thoracic Surgery (EACTS). In: Eur Heart J . No. 36 , 2015, p. 2921-2964 .