EGRAC

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EGRAC (English erythrocyte glutathione reductase activation ) is the abbreviation for the medicine common and in animal experiments erythrocytes - glutathione whose determination reductase activity coefficient by a EGRAC test a riboflavin (vitamin B2 deficiency) or FAD indicates deficiency.

The EGRAC test allows an objective statement to be made about the nutritional status of humans in field and therapeutic studies on diseases caused by malnutrition . Malnutrition can be quantified because the riboflavin and FAD levels correlate with the nutritional status. Riboflavin is mainly found in high-quality foods such as meat or grain sprouts and is reduced in case of malnutrition or malnutrition. The proportion of holo-glutathione reductase in total glutathione reductase also correlates with the FAD level. When assessing malnutrition, body weight and the overall impression of the person concerned are not sufficient and can be misinterpreted.

Individual evidence

  1. ↑ K. Becker, B. Krebs, RH Schirmer: Protein-chemical standardization of the erythrocyte glutathione reductase activation test (EGRAC test). Application to hypothyroidism. In: Int J Vitam Nutr Res. 61 (2), 1991, pp. 180-187. Erratum in: Int J Vitam Nutr Res. 61 (4), 1991, p. 376. PMID 1917356 .
  2. ↑ Y. Dror, F. Stern, M. Komarnitsky: Optimal and stable conditions for the determination of erythrocyte glutathione reductase activation coefficient to evaluate riboflavin status. In: Int J Vitam Nutr Res. 64 (4), 1994, pp. 257-262. PMID 7883462 .

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