Focal nodular hyperplasia
| Classification according to ICD-10 | |
|---|---|
| D13 | Benign new formation of other and imprecisely designated parts of the digestive system |
| D13.4 | liver |
| K76.8 | Other specified diseases of the liver |
| ICD-10 online (WHO version 2019) | |
The focal nodular hyperplasia (FNH) is a benign growth in the liver and often affects women (75%). A connection with the use of contraceptives is suspected.
pathology
Star-shaped scars, ribbon-like fibrous septa and bile duct proliferates are typically found. The growth ( hyperplasia ) usually has no connective tissue capsule.
Diagnosis
In sonography , the findings are usually isoechogenic to the rest of the liver tissue. When an ultrasound contrast agent is added, the wheel-spoke-like vascular supply is shown. Due to the isodense or isointense behavior in computed tomography or magnetic resonance tomography , the finding is difficult to discover. After the administration of contrast media with water-soluble contrast media, a strong marginal contrast medium enhancement with central hypodensity or hypointensity can be seen in these procedures. By using bile-permeable contrast media (Gadoxetic Acid = Primovist (R)), differentiation can be achieved in magnetic resonance tomography in a late phase with high sensitivity. [1]
clinic
Focal nodular hyperplasia often causes no symptoms and is often an incidental finding. Otherwise a feeling of pressure in the upper abdomen can be impressive.
therapy
As a rule, only the follow-up is indicated. If symptoms arise, the hyperplasia can be surgically removed. The majority of FNH patients have taken contraceptives containing estrogen; However, discontinuation or continuation of this medication has no effect on the growth of the FNH in the majority of patients.
swell
- Böcker, Denk, Heinz. Pathology . Munich 1997 ISBN 3-541-15891-3
- Herold G. Internal Medicine . Cologne 2012
supporting documents
- ↑ Herold G et al., Internal Medicine, p. 551.
