Frog dose

The frog dose (FD) is an outdated unit. It used to be used to determine the effectiveness of cardiac glycosides (e.g. digitalis ). A tree frog is injected with the smallest amount of the active substance to be determined into the breast lymph sac and it is determined whether a cardiac arrest occurs. This form of effectiveness determination was no longer used from the 1950s onwards due to the storage of defined quantities of digitalis.

See also

• Guinea pig unit

literature

• Hunnius Pharmaceutical Dictionary . CD-ROM edition (together with Pschyrembel clinical dictionary ), de Gruyter, Berlin 2004, ISBN 3-11-018201-7