Hematopoietic precursor cell antigen CD34
| Hematopoietic precursor cell antigen CD34 | ||
|---|---|---|
| other names |
CD34, Hematopoietic progenitor cell antigen CD34 |
|
| Properties of human protein | ||
| Mass / length primary structure | 385 amino acids , 40,716 Da | |
| Identifier | ||
| External IDs | ||
CD34 is a surface protein and cell adhesion molecule .
properties
CD34 is a sialomucin and is produced by hematopoietic progenitor cells and endothelial cells of various tissues . In the bone marrow, it binds hematopoietic stem cells to the extracellular matrix or to stromal cells . It binds selectins and is glycosylated and phosphorylated .
Web links
Individual evidence
- ↑ SG Furness, K. McNagny: Beyond mere markers: functions for CD34 family of sialomucins in hematopoiesis. In: Immunologic research. Volume 34, Number 1, 2006, pp. 13-32, doi : 10.1385 / IR: 34: 1: 13 , PMID 16720896 .