Hepatization
Hepatization (also Verleberung ) describes the transformation of lung tissue in the lobar pneumonia in an appearance, the liver tissue (liver Greek: ἧπαρ - Hepar) is similar. This change occurs as a result of lobar pneumonia or typical pneumonia after the coupling. Fibrin , erythrocytes and other cells that compact the lung tissue look macroscopically similar to liver tissue in the pathological section .
There are several stages of hepatization that can be converted back into healthy tissue .
Catching up (1st - 2nd day)
The general inflammatory reaction with vascular permeability results in a dark red coloration of the tissue and the tissue becomes heavy and less airy. At this stage the content is still liquid and flows off if you cut into it (during an operation or autopsy).
Red hepatization (2nd - 3rd day)
In this first stage of hepatization, the blood increasingly coagulates and solidifies.
Gray hepatization (4th - 6th day)
At this second stage, most of the erythrocytes are already dissolved and the lungs turn gray due to migrating white blood cells and an increased fibrin content.
Yellow hepatization (7th-8th day)
In the last stage, pus develops , which determines the color of the tissue.
From now on the tissue can be completely regenerated ( restitutio ad integrum ), as the mass liquefies and can also be coughed up as cloudy sputum (lysis) .
Individual evidence
- ↑ a b c C. Thomas: Special Pathology. Schattauer Verlag, 1996, ISBN 3-7945-1713-X , p. 118. (books.google.de)