Heat shock protein β-7
| Heat shock protein β-7 | ||
|---|---|---|
| Properties of human protein | ||
| Mass / length primary structure | 170 amino acids | |
| Isoforms | 3 | |
| Identifier | ||
| Gene name | HSPB7 | |
| External IDs | ||
| Occurrence | ||
| Homology family | HSPB7 | |
| Parent taxon | Vertebrates | |
The heat shock protein beta-7 ( gene name: HSPB7 , formerly cvHSP) is a protein found in vertebrates . It belongs to the group of so-called small heat shock proteins , whose characteristic feature is the α-crystallin domain.
cvHSP was published in 1999 by Krief et al. described, consists of 170 amino acids and appears to be expressed only in cardiac and skeletal muscle tissue . Analyzes with the yeast two-hybrid system and immunoprecipitation experiments showed that cvHSP is linked to alpha- filamine . The amino acids with the sequence numbers 56 to 119 seem to be decisive for this protein interaction . It has been shown that cvHSP also interacts with the small heat shock protein HSP22 (HSPB8).
swell
- ↑ Krief, S. et al. (1999). Identification and characterization of cvHsp. A novel human small stress protein selectively expressed in cardiovascular and insulin-sensitive tissues. In: J Biol Chem . 274 (51): 36592-600; PMID 10593960 ; PDF (free full text access)
- ↑ Sun, X. et al. (2004). Interaction of human HSP22 (HSPB8) with other small heat shock proteins . In: J Biol Chem 279 (4): 2394-402; PMID 14594798 ; PDF (free full text access)