Imidazole alkaloids
Imidazole alkaloids are a group of alkaloids whose basic structure contains the imidazole ring system .
Occurrence
In nature they occur both as secondary plant substances and in marine organisms as a by-product of the histidine metabolism . A well-known imidazole alkaloid is the pilocarpine found in Paraguay Jaborandi leaves .
Various monomeric imidazole alkaloids such as semilepidinoside A and semilepidinoside B as well as dimeric forms such as lepidines B, C, D, E and F can be isolated from the seeds of the garden cress ( Lepidium sativum ) . Various imidazole alkaloids such as 2-deoxy-2-aminokealiquinone and Naamin C could be detected in the sponge Leucetta chagosensis . Imbricatin was isolated from the starfish Dermasterias imbricata , while martensin A was isolated from the red alga Martensia fragilis . The sea sponge Pseudaxinyssa contains odilin.
Representative
A well-known imidazole alkaloid is pilocarpine . Other representatives include a. Cynodine , Cynometrine and Odiline .
Web pages
- Imidazole alkaloids . In: Lexicon of Biochemistry , at Spektrum.de. Retrieved September 29, 2019.
Individual evidence
- ↑ a b c Entry on imidazole alkaloids. In: Römpp Online . Georg Thieme Verlag, accessed on May 27, 2020.
- ↑ Ulrich H. Maier, Heidrun Gundlach, Meinhart H. Zenk: Seven imidazole alkaloids from Lepidium sativum. In: Phytochemistry. 49, 1998, pp. 1791-1795, doi : 10.1016 / S0031-9422 (98) 00275-1 .
- ↑ Xiong Fu, John R. Barnes, Trang Do, Francis J. Schmitz: New Imidazole Alkaloids from the Sponge Leucetta chagosensis. In: Journal of Natural Products. 60, 1997, pp. 497-498, doi : 10.1021 / np960694i .