Inanition icterus

The Inanitionsikterus represents a special form of jaundice (jaundice) during animal represents.

The disease is characterized by an increase in the concentration of bilirubin in the blood ( hyperbilirubinemia ). This is created by mobilizing the fat reserves. The free fatty acids released as a result displace bilirubin I on the albumin in the blood and on the transport proteins ligandin (Y protein) and Z protein in the liver cells .

Since the actual trigger is fat mobilization, an increased bilirubin content indicates a reduced or completely stopped feed intake. In the case of moderately to severely elevated bilirubin concentrations, however, inanition icterus is unlikely. Hemolytic processes are more likely then.

Bile acids and various drugs also compete for transport with bilirubin.

In cattle, bilirubin concentrations between 5 and 20 µmol / l can be interpreted as inanition icterus.

literature

• W. Kraft, UM Dürr (ed.): Clinical laboratory diagnostics in veterinary medicine, 6th edition, Schattauer, Stuttgart 2005, p. 158
• N. Zahn, Dissertation: Metabolic investigation in clinically healthy cows with special consideration of superoxide dismutase, Leipzig 2006, p. 8